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Importantly, we recommend that animal and cell-based models rely on multiple risk factors to mimic the events at different stages of dry AMD, and that multiple models should be utilized to deepen the rigor beyond what a single model will provide

Rescue medication was available for patients whose fasting plasma glucose exceeded the predefined limits of 15.0 mmol/L from week 8, 13.3 mmol/L from week 9 to week 20, and 11.1 mmol/L from week 21 to week 32

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Cancer Epidemiology Biomarkers & Prevention

10.1186/s13024-021-00456-1 Mol

Upregulation of endothelial heme oxygenase-1 expression through the activation of the JNK pathway by sublethal concentrations of acrolein