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[76] found that butyrate treatment significantly alleviated diarrhea in piglets co-infected with ETEC F4 and ETEC F18 by reducing neutrophil infiltration and lowering serum TNF- levels

Thus, it has been proposed that mutSOD1 exerts its deleterious effect by a toxic gain of function rather than by altered SOD1 activity, given the lack of correlation between SOD1 dismutase activity and aggressiveness of clinical phenotypes[86] and since SOD1 knockout mice do not develop the ALS phenotype per se[87]

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Cathartic therapy (not proven effective, but rational): Lactulose

P.WilliamsK

Genes exhibiting false discovery rate (FDR)-adjusted P 2 were considered significant and subjected to further analysis