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The protocol involves a loading phase, a weight loss phase with HCG injections, and a maintenance phase

(iv) display of ataxia

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Preclinical in vivo evidence: energy expenditure, substrate selection, and adiposity In chow-fed mice kept at thermoneutrality, repeated SLU-PP-332 administration increases energy expenditure, lowers RER (favoring fat over carbohydrate oxidation), and reduces adipocyte size, without changing food intake or spontaneous locomotor activity

Protein enrichment analysis showed that DPI and MitoQ single treatments induced a similar profile of downregulated peptides, affecting mainly members of the complex I of the mitochondrial respiratory chain and cell cycle/division proteins ( Supplementary Figures S3 , S4

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