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(2008) Journal of Orthopaedic Research Rat model of articular cartilage defect treated with local and systemic AOD 9604 measuring cartilage repair and collagen synthesis

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For the positive control, dots coated with 7 g of His-tagged CspZ were incubated with anti-His antibody-FITC conjugate (1:500 diluted in PBS), then incubated for 1 hour at 37 C

Normal post-injection inflammation peaks within 6 hours and produces erythema 2cm diameter without warmth

A bone spur develops for a number of reasons including: Foot mechanics Injury or Trauma Arthritis The bone spur builds up over a joint and forms a point on top of the foot