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mean PFS of 9.1 versus 7.1 months

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Heavy smoking was associated with a significantly increased risk of hypomethylation of Aryl-Hydrocarbon Receptor Repressor ( AHRR) gene, in line with numerous other reports of AHRR serving as an effective biomarker of tobacco smoke exposure

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Wang Z, Sun W, Sun X, Wang Y, Zhou M (2020d) Kaempferol ameliorates Cisplatin induced nephrotoxicity by modulating oxidative stress, inflammation and apoptosis via ERK and NF-B pathways

It activates PI3K/Akt and MAPK pathways, preventing neuronal death caused by amyloidogenesis, glucose deprivation, neuroinflammation, and apoptosis (8)