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Milk thistle is a food supplement, not a licensed medicinal product

Plant Sci 180:548553 Herbette S, Lenne C, Leblanc N, Julien JL, Drevet JR, Roeckel-Drevet P (2002) Two GPX-like proteins from Lycopersicon esculentum and Helianthus annuus are antioxidant enzymes with phospholipid hydroperoxide glutathione peroxidase and thioredoxin peroxidase activities

Polymorphisms of glutathione S-transferase genes (GSTM1, GSTP1 and GSTT1) and breast cancer susceptibility

Mol Aspects Med 30 , 1-12 (2009)

The TCM and natural products, as mentioned above, can regulate immune cells, immune-related pathways, intestinal flora, improve intestinal barrier function, regulate oxidation, autophagy, and angiogenesis

Consequently, there is a necessity to investigate the effect of glutamine metabolism and NK cell interaction on the proliferative effects of cancer cells in a more in-depth and broader systematic manner through multidimensional modeling and the integrated use of multiple biological approaches