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Adverse Reactions/Side Effects Mild transient diarrhea, polycythemia vera, peripheral vascular thrombosis, itching transitory exanthema, feeling of swelling of entire body, anaphylactic shock and death

Alterations of bone biomechanical properties can contribute to osteoporosis and increase the risk of fractures in the elderly

Severe deficiencies may lead to anemia and nerve damage if left untreated

Niacin/niacinamide may potentiate the effects of antihypertensive medications by causing additional vasodilation

For example, older people (because absorption declines with age) and those with gut-related conditions such as celiac disease and Crohns disease may struggle to absorb enough vitamin B12 to stave off symptoms of a deficiency, says Foxx

Its always a good practice to inform your healthcare provider about all medicines, vitamins, and supplements you are using