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The Kolonin mouse study that started everything In 2004, Mikhail Kolonin and colleagues published a landmark study in Nature Medicine titled "Reversal of obesity by targeted ablation of adipose tissue." This was the paper that introduced the world to vascular-targeted fat destruction

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Cardiovascular disease The number of deaths attributed to heart failure is increasing worldwide and has become a global health issue

This metabolic alteration results in enhanced activation and differentiation of T-cells, culminating in the excessive production of pro-inflammatory cytokines, such as IFN- and TNF-

2015;69(6):563-567 Karnehed N

Treatments can be given once or twice a week and a treatment programme usually consists of 3 or 5 sessions