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10.1161/CIRCRESAHA.123.322806 158 NoelsH.LehrkeM.VanholderR.JankowskiJ

Adaptive and maladaptive cardiorespiratory responses to continuous and intermittent hypoxia mediated by hypoxia-inducible factors 1 and 2

Blatter, S

The EGF receptor interacts with the type 1 IGF receptor and regulates its stability

It has multiple anticancer mechanisms, not only blocking EGFR and MET-mediated signaling, but also directing immune cells to target tumors harboring activating and resistant EGFR/MET mutations and amplifications

As personalized medicine evolves, regulatory considerations and policy frameworks will be critical in ensuring patient safety, efficacy, and access to innovative therapies