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10.1016/j.jff.2016.06.032 J

PLoS Comput Biol 14:e1006146

Improvements in mood, sleep, and energy may appear within weeks, while visible benefits like improved skin, muscle tone, and bone density may take 36 months

Proteomic analysis was performed to identify differentially expressed proteins (DEPs), while metabolomic profiling was used to characterize metabolic changes