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Science of the Total Environment, 615 , 131-140

They can improve skin quality over time but are not a miracle solution and should not replace treatments like retinoids

10.1016/j.jep.2024.118425 [DOI] [PubMed] [Google Scholar] Hu S., Li A., Huang T., Lai J., Li J., Sublette M

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In animals, sleep deprivation also leads to upregulation of -secretase 1 (BACE-1), the most important enzyme regulating A generation in the brain 142,143,149 , thus opening the hypothesis of increased A production by sleep deprivation