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This pigment helps brighten the skin and gives it a natural pinkish-red hue, enhancing its overall beauty

It also plays a vital role in collagen synthesis, promoting skin elasticity and reducing the appearance of wrinkles

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Notably, PD patient substantia nigra samples reveal approximately 80% reduction in CP activity, correlating with aggravated iron deposition and DA neuron death

Intestinal inflammation is further investigated by determining calprotectin levels in caecum content using the Immundiagnostik S100A8/S100A9 ELISA kit (Immundiagnostik, Bensheim, Germany)

Mitochondrial ferritin (FtMt), a mitochondria-localized iron storage protein with iron-binding affinity comparable to cytosolic ferritin [80], contributes to the maintenance of mitochondrial iron homeostasis [81]