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In summary, our study showed no clear association of serum IGF-1 concentration with ALS risk but with the prognosis of ALS, suggesting that higher IGF-1 concentration could increase survival

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If the depressed oxygen consumption caused by NNMT overexpression indicates the depression of aerobic metabolism, the regulatory effect of NNMT on anaerobic metabolism might be reversed

The severity of the deficiency, any health conditions, and how well the treatment works are all important

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