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First, enriched with Th1-like signatures in CD4+ T cells, M1-like pro-inflammatory signatures in monocytes, cytotoxic effector signatures in CD8+, T cells and NK cells, and memory signatures in B cells

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A metabolite of linoleic acid, 10-hydroxy-cis-12-octadecenoic acid (HYA), inhibits TNF- expression and DSS-induced alterations in the expression of TJs such as occludin, zonula occludens-1, and myosin light chain kinase

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