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Virus-mediated knockdown of HDAC2 can also restore structural and synaptic plasticity, ultimately improving memory loss associated with neurodegenerative diseases 144,145

doi: 10.1038/ng.601 209 RaghupathyRHuiEPChanAT

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Oxidized phosphatidylcholines found in multiple sclerosis lesions mediate neurodegeneration and are neutralized by microglia

These will likely include approaches targeting both aberrant neuronal function, as well as pathological processes such as inflammation that may indirectly affect sensory systems