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The activation of AMPAR, particularly GluR1 and GluR2 subunits, induced a switch to invasive and migratory phenotype, via activation of the K-ras/MAPK cascade ( Figure 3 )

FIGURE 2 3 Oxidative DNA damage and epigenetic mark Eukaryotic cells have developed incredibly complex methods to promptly adjust the expression of their genes in response to environmental changes

Indeed, our findings suggest that l-Cit supplementation before exercise can be an effective antioxidant agent that enhances SOD, GPx and CAT through its antioxidant properties