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2.4 The ferroptosis-inflammation vicious cycle drives chronic periodontitis Growing evidence indicates that ferroptosis can trigger inflammatory responses, while the inflammatory microenvironment further promotes ferroptosis, forming a self-amplifying vicious cycle that drives the persistent progression of chronic periodontitis

Being water-soluble, excess B12 is typically excreted through urine

It is important to note that mitochondrial composition in tumors is highly heterogeneous, and both metabolic demands and genetic backgrounds differ markedly from those observed in inherited mitochondrial disorders

MYB-RELATED TRANSCRIPTION FACTOR A transcription factor that contains a DNA-binding domain that shows sequence similarity to vMYB, the first-described member of this family

It neutralizes reactive oxygen species (free radicals) and helps protect cells from oxidative stress, which can damage DNA, proteins, and cellular membranes

Insulinregulated aminopeptidase inhibitormediated increases in dendritic spine density are facilitated by glucose uptake