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An in vitro study of human bronchial epithelial cells from patients with COPD or asthma showed that increased oxidant burden may lead to reduced corticosteroid responsiveness in airway epithelium, with important consequences for the integrity of the epithelial barrier and associated production of pro-inflammatory cytokines [43]

The limit of detection and limit of quantitation were found to be 0.0001 mg/ml and 0.00018 mg/ml for NAC, and 0.00015 mg/ml and 0.00045 mg/ml for DI-NAC

Widjaja CE, Olvera JG, Metz PJ, Phan AT, Savas JN, de Bruin G, et al

doi: 10.1080/13813455.2021.1893338 68 KangK-WOkMLeeS-K

Myofibroblasts and fibrosis: Mitochondrial and metabolic control of cellular differentiation

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