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TABLE 1 Main MGBA components and signaling pathways

Beta-adrenergic GPCRs couple to a stimulatory G-protein, or G s , which initiates the cyclic AMP (cAMP) second messenger system by activating the enzyme adenylyl cyclase

The physical barrier function is mainly performed by the corneocytes, while the water permeability barrier is achieved by the lipid matrix

Inclusion criteria included anterior circulation stroke, DECT within 3h post-EVT, and follow-up imaging performed after DECT