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however, the amount of -lipoic acid inside the body decreases significantly with age, resulting in endothelial dysfunction

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Besides, elderly people supplemented with folic acid (400 ug/day) had significantly stronger natural killer cells (NK cells) function and were less susceptible to infections than their peers who were not supplemented with folic acid (102)

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And it plays a role in buffering the mitochondrial acyl-CoA pool, helping maintain metabolic flexibility, the ability to switch between fat and carbohydrate as fuel sources depending on demand

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