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Adenoviral gene transfer of E2F-1 induces apoptosis through upregulation of the DSRNA activated protein kinase PKR

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The most common disruption of this pathway leads to hyperhomocysteinemia (HHcy), a well-known risk factor for the development of cardiometabolic diseases and other pathological conditions

Rela M, Rammohan A, Rajalingam R, Clavien PA

The findings indicated that nanoencapsulation is a powerful tool for delivering curcumin, regulating metabolic pathways, and protecting vital organs, such as the kidneys, from inflammation-related damage [143]

Experimental studies focus on receptor binding characteristics, signal transduction dynamics, and pathway modulation under controlled conditions