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Some potential mechanisms for involvement of the microbiota include inflammation induced by low-grade endotoxemia, increased energy harvest from food, altered fatty acid metabolism, and variations in gut-derived peptide secretion

Growth hormone acts directly on adipocytes to increase lipolysis and on hepatocytes to stimulate gluconeogenesis, but its anabolic and growth-promoting effects are mediated indirectly through the induction of IGF-1

SST is an endocrine inhibitory hormone, with its brain derivative, SST-14, expressed throughout the cortex 56

It doesn't introduce a foreign substance to get the job done

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