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Since COXP contains a cholesterol structure and cholesterol is one of the major components of liposomes, we used COXP to prepare COXP liposomes in the anticipation that the hydrophilic GSH of COXP would orient itself on the surface of the liposomes for brain targeting (Fig

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For example, individuals with a high level of CD19 + cells in the bone marrow prior to CAR T cell therapy had a greater magnitude of CAR T cell persistence post-remission, which correlated with a reduced risk of CD19 + disease relapse 3133