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Tumor dimensions (length and width) and body weight were measured using a caliper every two days, and tumor volumes were calculated using the following formula: At the end of the experiment, the mice were euthanized, and whole blood, heart, liver, spleen, lungs, kidneys, tumor-draining lymph nodes (TDLNs), and tumors were harvested for imaging and weighing

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The key is to focus on strategies that respect your bodys limits and can be tracked over time

IRE1alpha prevents hepatic steatosis by processing and promoting the degradation of select microRNAs

Metabolic activity, namely glycolysis and oxidative phosphorylation, are drivers of immune cell function