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Activation of the Hedgehog signaling molecule promotes clonogenicity of SCLC in vitro and accelerates the initiation and progression of SCLC in mice in vivo

Pooled analysis of the studies showed a significant decrease in systolic 24-hour ABP at 12 months compared to baseline, with MD of 13.42 mm Hg ( p = 0.0007) and a I 2 value of 73% (Fig