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Introduction The transcription factor (nuclear factor-erythroid 2 p45-related factor 2, NRF2) is a master regulator of the cellular response to oxidative insults

To limit potentially life-threatening depletion of intracellular antioxidant/GSH stores, epithelial cells have developed numerous compensatory pathways, including the cystine-glutamate antiporter (SLC7A11), which critically maintains de novo GSH biosynthesis by increasing intracellular cystine levels (9)

by Hannah de Gruchy February 10, 2022 Methylsulphonylmethane, or MSM, is a supplement that when paired with vitamin C, has real health benefits

doi: 10.1089/152460900750020937

Oncotarget 7 , 67116726 (2016)

doi: 10.1016/j.afres.2021.100021 170 BashmilYMAliABkADunsheaFRSuleriaHA