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The hair-relevant evidence discussed here is predominantly in vitro or ex vivo, and much of the most-cited follicle data was generated with the related peptide AHK-Cu rather than GHK-Cu

Neuroprotection from injury cascades After a neurological injury such as stroke, TBI, or the chronic damage seen in neurodegeneration a cascade of secondary injury events unfolds: excitotoxicity, uncontrolled apoptosis, oxidative stress, and neuroinflammation

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For example, in 2015, a randomized clinical trial of elderly men with sarcopenia found that 15g of daily collagen peptide supplementation, in combination with resistance training, led to improvements in multiple parameters: muscle strength, fat mass, and fat-free mass.40 For another example, a 2023 study of subjects with ultrasound-confirmed musculoskeletal inflammation concluded that locally injected collagen peptides could effectively and safely treat collateral ligament pain, indicating positive implications for physical recovery.41 It isnt clear how collagen compares to other peptides in facilitating these outcomes, as head-to-head studies arent available

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