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Controlled studies in healthy adults consistently show a reduction in T3 with a compensatory increase in T4, generally reflecting an adaptive rather than a pathological response [12,132]

[PubMed] [Google Scholar] [84].Hermanson G, Bioconjugate techniques, 1st ed, Academic Press, San Diego, CA, 1996

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TCP is also an option, in case the client/server implementations reside on different hosts and the deliverability of metrics is a primary concern