glutathione lupus treatment Frontiers 15 Glutathione Benefits: How to

I.PiluduM.et al (2021)

10.1007/s10067-020-05178-1 114 KumarA.SinghB.MishraJ.SahS

doi: 10.3389/fmolb.2022.859760 121 SapoK.MakaR.JanasT.JanasT

Abbreviations ACE: angiotensin-converting enzyme ACh: acetylcholine ADMA: asymmetric dimethyl-L-arginine ATII: angiotensin II BH 4 : tetrahydrobiopterin cGKI: cGMP-dependent protein kinase cGMP: cyclic guanosine monophosphate CTP CH-I: GTP cyclohydrolase I DDAH: dimethylarginine dimethylaminohydrolase DETC: diethylthiocarbamate DHFR: dihydrofolate reductase DOCA: deoxycorticosterone acetate eNOS: endothelial nitric oxide synthase FMD: flow-mediated dilation LDL: low-density lipoprotein L-NAME: N G -nitro-L-arginine methyl ester NO: nitric oxide NTG: nitroglycerin ONOO : peroxynitrite PDE1A1: phosphodiesterase 1A1 PKC: protein kinase C PRMT: protein arginine N -methyltransferase ROS: reactive oxygen species sGC: soluble guanylyl cyclase SHR: spontaneously hypertensive rats SNP: sodium nitroprusside SOD: superoxide dismutase STZ: streptozotocin VASP: vasodilator-stimulated phosphoprotein

These toxicities are mostly due to the conditioning regimen used prior to HSCT and several strategies have been introduced to improve the clinical outcome 23,24,25,26,27,28,29,30,31

Additionally, during the post-treatment period, mean severity scores of problematic behaviors decreased