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Prevalence of specific combinations of polysubstance use disorders Among US adults in the past year, 76.2% (95% CI = 75.776.6%) had no SUD, 17.6% (95% CI = 17.218.0%) had 1 SUD, 4.6% (95% CI = 4.44.9%) had 2 SUDs, and 1.6% (95% CI = 1.51.8%) had 3 SUDs (Supplementary Table 2)

[52] In view of the shortage of evidence, vaping is not recommend for cancer patients, although for all patients vaping is likely less dangerous than smoking cigarettes

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These VLN based products are the first and only combusted tobacco products to comply with the FDA's proposed new Tobacco Product Standard for Nicotine Yield of Cigarettes and Certain Other Combusted Tobacco Products

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