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Journal reference: Brody, A
The Continuous Abstinence Rate from Week 13 through Week 24 was higher for patients continuing treatment with CHANTIX (70%) than for patients switching to placebo (50%)
Polyubiquitin chains can be classified into eight distinct types (K6, K11, K27, K33, K48, K63, M1), with K48-linked ubiquitin chains, (requiring a minimum of four ubiquitin proteins) being recognized by the 26 S proteasome, leading to the degradation of the substrate protein