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Health Tip on Smoking Can Cause Colitis, Crohn's Disease Smoking and the Digestive System Johns Hopkins Medicine Think Smoking Only Affects Your Lungs? Think Again. Your digestive system takes a major hit too. Smoking can weaken your gut lining, slow down digestion, and increase the risk of ulcers and Smoking does not just impact your lungs. It alters your internal systems in ways that are often overlooked. The chemicals in cigarette smoke disrupt the balance of your gut microbiome, increase inflammation Frontiers Effect of Cigarette Smoke on Gut Microbiota: State of Knowledge Smoking and IBS
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