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Among individuals with PD, 21,880 (77.95%), 4653 (16.58%), and 1535 (5.47%) were never-, ex-, and current smokers, respectively

To gather relevant publications, we searched several databases such as PubMed, EBSCO, Cochrane, and Science Direct, using specific MESH terms and keywords such as cigarette smoking, air pollution, particulate matter, gaseous air pollutants, cardiovascular diseases, and hypertension. To ensure the quality of the studies, we applied PECOS criteria that focused on the population (i.e., adults chronically exposed to outdoor air pollutants), comparator (unexposed persons), result (all-cause mortality and cardiovascular diseases), and study design (experimental and epidemiological studies, intervention studies, meta-analyses, and systematic reviews published in peer-reviewed journals in English)

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Located in the lush region of Puriscal, Costa Rica, this factory is known for its meticulous craftsmanship, attention to detail, and passion for quality tobacco

And their new strategy seems to be working to an extent

(Publication type) Peer-reviewed original research articles