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The amount of nicotine present in cigarettes stimulates the nervous system and can temporarily speed up bowel activity but chronic smoking disturbs the balance of gut microbiota, which is essential for healthy digestion

Reality Several persistent myths suggest pipe smoking is substantially safer than cigarettes, especially without inhalation

Furthermore, KEGG pathway and Gene Ontology (GO) enrichment analyses were performed on the identified targets to systematically explore the associated biological processes, molecular functions, and signaling pathways

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