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It should be a baseline condition for public health

2019;316(5) doi: 10.1152/ajplung.00492.2018

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Smoking accounts for 33% of all deaths from cardiovascular disease and 20% of deaths from ischemic heart disease worldwide [ 60 ]

(For a thorough comparison of emissions from heated tobacco products, e-cigarettes, and conventional cigarettes, see this recent review.) But even if heated tobacco compares favorably in a one-to-one comparison to conventional cigarettes, how people use it matters too