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In 1973, the figure rose to about five hundred and eighty-five billionthe biggest annual consumption of cigarettes in history

These parameters indicate the ambient exposure to and frequency of smoking, as well as the potential damage caused by inhaled smoke

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On average, smokers absorb 1 to 2 mg of nicotine per cigarette, depending on factors like puff duration, depth of inhalation, and the cigarette brand

Together, the results of this study suggest that reduction of p23 expression may protect normal airway epithelial cells from some of the damaging effects of cigarette smoke

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