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In both diseases the disturbed lipid metabolism in hepatocyte leads to intracellular build-up of potentially toxic bioactive lipid species causing endoplasmic reticulum (ER) stress, mitochondrial dysfunction and cellular death, which in turn triggers the innate immune response and activation of hepatic stellate cells (HSCs), resulting in inflammation and increased collagen production and deposition

It is often associated with tropical regions like the Caribbean and South America

For respiratory mortality, there was a clear effect of smoking, but little effect of drinking

PLoS Med

Oncology patients' perception of physicians who use an integrated electronic health record (EHR) during clinic visits: PRIME-EHR double-blind, randomized controlled trial

The telomere protects the DNA from damage each time the cell divides, but in the process of every cell division the telomere gets a bit shorter