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(Note that the rules around internal defibrillators (ICDs) and driving are more stringent.) For more detail, you may find this article helpful: Driving in Ireland when you have a pacemaker

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PMID 22375280

In a statement quoted in the article, the FDA explained that, based on current data, the two approved Vuse cartridges are significantly less toxic than traditional cigarettes and offer a potential benefit to people who may use them to stop smoking

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Long-term exposure to these irritants can lead to persistent throat issues and an increased risk of throat cancer