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On the other hand, the self-medication hypothesis leads to concerns that aggressively treating smoking may worsen the symptoms of other mental disorders (including other SUD) (111)

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Japan Tobacco, which commands about 60 percent of Japan's cigarette market and is the world's third-largest tobacco maker, has also got in on the action by acquiring two overseas e-cigarette makers in the past two years

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"Thinking positive is the best thing you can do," Nelson says

It was a very frustrating four years," Zeller said