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Gum Inflammation and Recession Nicotine may constrict blood vessels, causing gums to recede and increasing the risk of disease in the gums

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Switch to Freebase E-Liquids: Freebase nicotine e-liquids typically deliver nicotine less rapidly and at lower concentrations, which may reduce the risk and severity of side effects

Several states have instead built product directory systems, which are state-maintained approved lists that determine which products can legally be sold

According to PMI, IQOS are also 95% less toxic than traditional cigarettes (Figure 5)