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Most tobacco products, including e cigarettes, contain nicotine, a chemical that can harm the heart, brain and whole body. As with other addictive products, using a nicotine product builds tolerance, leading to more Biological determinants impact the neurovascular toxicity of nicotine and tobacco smoke: A pharmacokinetic and pharmacodynamics perspective ScienceDirect What Is Nicotine and Its Side Effects on the Body and Brain Side Effects of Nicotine on Your Health Why is smoking bad for you? Smoking: Effects, Risks, Diseases, Quitting & Solutions
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