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While early reports have also described a connection between acute e-cigarette use and biomarkers linked to elevated cancer risk, there is limited evidence at this point to suggest a direct causal association between ENDS usage and cancer development [144]

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However, the report also warns that tobacco and nicotine products are becoming more affordable despite recent tax hikes, a trend that could particularly affect teenagers and young adults, who are considered especially sensitive to price changes

Altogether, these data suggest that e-cigarette exposure reduces cisplatin uptake and retention, thereby decreasing the formation of platinumDNA adducts and consequently reducing cisplatin cytotoxicity