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The present study supports these findings as glycolysis in ARPE-19 cells was also shown to depend on HIF-1 signaling under normoxic conditions

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Considering that CD development may be accompanied by multifocal microinfarcts in the gastrointestinal tract (76, 77), it seems logical that cigarette smoking can worsen the disease by increasing endothelial dysfunction

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The past decade has brought new issues regarding cigarettes, when electronic cigarettes, also known as e-cigarettes or vaping pens, were introduced as a bridge to help individuals quit tobacco cigarettes