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In the United States, smoking rates have fallen by 50 percent since their peak in the 1960s as a result of tobacco control policies, but smoking still contributes to high rates of premature mortality, the authors write

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Despite higher nicotine levels, tobacco reduction markedly improved myocardial perfusion, suggesting that combustion products rather than nicotine were the primary contributors to smoking-induced cardiac ischemia

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Strahan, E

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