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It primarily manifests as ulcerative colitis (UC) or Crohns disease (CD), distinguished by differences in disease location, histopathology, and clinical presentation

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Chronic exposure to CS manifests as pathological changes like heightened oxidative stress, increased lung permeability, loss of tight junctions, epithelial-mesenchymal transition (EMT) all of which contributes to tissue destruction and impaired lung function 4,5,6