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The 2015 Health and Risk Behaviors of Massachusetts Youth study found that 23.7 high school students had used an electronic vapor product in the past 30 days and nearly 45 percent reported ever using such a product

for some, the flavor of cigarettes is tied to relaxation, while for others, its the perfect pairing for a drink or a deep conversation

The segment shows resilience despite declining overall smoking rates

In addition, our main single variable analyses included multiple MR methods, each relying on orthogonal assumptions, which provide confidence in robustness of the results and strengthen causal inference 46

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Latin America and the Caribbean accounted for the largest share of records (40.1%), followed by Asia (26.1%), Europe (26.0%), Africa (5.8%), and North America (1.8%) (Fig