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Electronic Cigarettes and Vascular Function The link between combustible tobacco product usage, vascular endothelial dysfunction, and subsequent cardiovascular disease development is well documented [106]

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"Any agent that provides a gateway towards tobacco use is something that needs to be addressed, and addressed rigorously." The new rules will require companies to disclose ingredients inside the nicotine-laced flavored fluids, and apply nicotine labels and warnings

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De Cunto G, Brancaleone V, Riemma MA, et al

There are many chemicals produced in cigarette smoke that might be responsible for vascular injury