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This is likely because estrogen moderates the release of norepinephrine, reducing activation of the HPA axis during a stressful event

Seek emergency medical care if confusion or poor concentration occurs suddenly and is accompanied by severe headache, difficulty speaking, facial drooping, weakness, seizures, loss of consciousness, or vision changes, as these may signal a stroke or another urgent neurological condition

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[10] They do not produce sidestream smoke or sidestream vapor