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Specific binding volume of distribution (V S /f P ), a measure proportional to 4 2 * nAChR density, was determined for regions known to have nAChR upregulation with smoking (prefrontal cortex, brainstem, and cerebellum)

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Therefore, cigarette smoking may influence oxidative stress by affecting the levels of plasma antioxidants, which may be involved in the mechanisms underlying various diseases

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Either way, hydration and kidney function make a big difference, because the more hydrated you are, the faster the body can flush residual cotinine, though overdoing fluids can dilute the sample (and raise a few eyebrows in the process)

But if you prefer a simpler, more subtle experience, the Clear flavor might be the perfect choice for you