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The sum of several decades of laboratory research lends experimental support to the epidemiologic observations that cancer, respiratory disease, cardiovascular disease, and other adverse health outcomes are causally related to cigarette smoking

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doi: 10.1136/tobaccocontrol-2020-056053

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Neutrophils were characterized by functional heterogeneity, including an interferon response driven subset, and identified as important early regulators and amplifiers of pulmonary inflammation